1. you were often manipulating hardware directly and had to set the bits in hardware registers. 
   我们经常都要直接操纵硬件，需要频繁设置硬件寄存器内的二进制位。
2. Are you manipulating the object directly, or are you dealing with some kind of indirect representation (a pointer in C or C++) that must be treated with a special syntax? 
   您曾利用一些特殊语法直接操作过对象，或处理过一些间接表示的对象吗(c或c++里的指针)？
3. The act or practice of manipulating. 
   操作操作的行为或实践
4. Blame beer gut on genes 
   基因导致啤酒肚？
5. A second application attack comes in manipulating SQL commands. 
   第二种应用程序攻击是出自对sql命令的控制。

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