Purpose To prepare 11 - deoxy - glycyrrhetinic acid.

目的制备 11- 脱氧甘草次酸.

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Objective To synthesize the novel derivatives of 11 - deoxy glycyrrhetinic acid with high anti - inflammatory activities.

目的合成新型的11-脱氧甘草次酸衍生物,寻找 抗炎 活性高的药物.

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ConclusionModified Clemmensen reduction was successfully used to prepare 11 - deoxy - glycyrrhetinic acid with high yield.

结论改进的克莱门森还原法制备 11- 脱氧甘草次酸收率较高,对环境友好,而且简便.

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Methods Reduction of the 11 - carbonyl group of glycyrrhetinic acid was done through modified Clemmensen reaction.

方法采用改进的克莱门森反应还原甘草次酸的11位羰基.

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