The inactivation of P 53 is associated with the acute transformation phase and development of CML.

P53基因失活与慢性粒细胞白血病的急变、病情进展密切相关.

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Objective To characterize the immunophenotype and cytogenetics of chronic myeloid leukemia blast crisis ( CML - BC ).

目的研究慢性髓细胞白血病急变期 ( CML-BC ) 的免疫表型特征及细胞遗传学特征.

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Con - clu sion : The inhibition of apoptosis may play a role in the blastic transition of CML.

结论: 细胞凋亡受抑可能在CML急变 形成过程中发挥一定的作用.

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