Objective To review the advances on lovastatin fermentation by Aspergillus terrus.

目的综述土曲霉洛伐他汀发酵研究的进展.

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Objective To construct one of yield lovastatin strain that is a very valid medicine for cholesterol - lowering.

目的探索构建洛伐他汀高产菌株的原生质体制备和融合方法.

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Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.

方法: 以洛伐他汀为原料,通过酰化 、 甲基化 、 水解、环合等反应合成了辛伐他汀.

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