RESULTS: Aristolochic acid has nephrotoxicity, alimentary canal toxicity, carcinogenicity, mutagenicity and genotoxicity.

结果: 马兜铃酸具有肾毒性 、 消化道毒性 、 致癌性 、 致突变性和基因毒性.

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Objective To discuss the main and signs of chronic aristolochine nephropathy ( CAN ) .

目的探讨慢性马兜铃酸 肾病 的主要中医证候.

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To establish a limiting detection for aristolochic acid A in Xiaoqinglong mixture.

目的:建立小青龙合剂中马兜铃酸A的限量检查方法.

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In addition, the pathology of the Aristolochinc Acid Nephropathy was briefly introduced.

同时对马兜铃酸肾病的病理表现做一简要的介绍.

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Objective To control the quantity of aristolochic acid in Xinmazhike Granules.

目的控制辛麻止咳颗粒中马兜铃酸的含量.

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Conclusion There is no aristolochic acid in Xinmazhike Granules.

结论该品中不含马兜铃酸.

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Asarum is an efficacious traditional Chinese medicine.

细辛(马兜铃科细辛属)为我国传统中草药,具有祛风散寒,通窍止痛,温肺化饮之功效,自古以来,一直被医家视为祛除痼疾的常用药.

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CONCLUSION: We should dialectically and rationally use Chinese crude drug containing the component of aristolochic acid.

结论: 要辨证合理使用含有马兜铃酸成分的中药材.

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METHODS: We analyzed the causes accountable for the renal toxicity of Aristolochic acid - containing Chinese medicines.

方法:分 析含马兜铃酸类中药引起马兜铃酸肾毒性的原因.

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Objective To research the content changes of Aristolochic Acid - A from Aristolochiae Manshuriensis and its processed products.

目的考察关木通药材及其炮制品中马兜铃酸A的含量变化.

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Food plant: mainly Cruciferae, Leguminosae, Rosaceae , Rutaceae, Aristolochiaceae , Annonaceae , Lauraceae , Apiaceae , Asclepiadaceae and dogbane, etc.

食用植物: 主要为十字花科 、 豆科 、 蔷薇科植物.芸香科 、 马兜铃科、蕃荔枝科 、 樟科、伞形花科等.萝摩科,夹竹桃等.

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Method Searching published literatures and website associated with aristolochic acid toxicities and abroad and analyzing them.

方法通过检索国内外公开发表的文献和各国官方网站,收集与马兜铃酸有关的不良反应病例,分析其安全性.

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To establish a HPLC method determination the content of Aristolochie acid A in Aristolochia debilis Sieb.

采用高效液相色谱法测定马兜铃中马兜A的含量.

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Methods HPLC was used to determine the content of aristolochic acid in Xinmazhike Granules.

方法采用高效液相色谱法建立了辛麻止咳颗粒中马兜铃酸的含量测定方法.

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Objective : To reconfirm the medicinal plants of Aristolochiaceae, Caryophyllaceae, Menispermaceae, Illiciaceae and Magnoliaceae found in Guizhou Province.

目的: 通过修订,确认贵州马兜铃科 、 石竹科 、 防己科 、 八角科和木兰科药用植物的种类.

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